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Martin Young, DPhil

Martin Young, DPhil
Department of Medicine
Vice Division Director of Research
Division of Cardiovascular Research
Zeigler Building, Room 308
1530 3rd Avenue South
Birmingham, Alabama 35294-0006
Email Address:   
Office Phone: (205) 934-2328 
Office Fax: (205) 975-5150
Full CV
Web Site

Research Interests

  • Pathogenesis of myocardial contractile dysfunction observed during obesity and diabetes mellitus
  • Influence of environmental factors (time-of-day & nutrition) on cardiovascular health and disease 
  • Cardiomyocytes and the circadian clock 
  • Humoral factors: nutrients (glucose & fatty acids)
  • Increased fatty acid availability and the accumulation of intramyocellular fatty acid derivatives


  • Postdoctoral Training: University of Texas-Houston, Boston University
  • Doctor of Philosophy (Biochemistry): University of Oxford
  • Master of Science: University of Oxford
  • Bachelor or Science: University of Oxford


Published on Mar 10, 2016
Upcoming Daylight Saving Time May Trigger Serious Health Issues - Dr. Young's interview with NBC nightly news

Published on Dec 4, 2018
Circadian Disruption: Heart Failure Risk Factor - Martin Young, MD, discusses circadian rhythms and how they affect cardiometabolic diseases including heart failure.


  1. Leighton B, Sanderson AL, Young ME, Radda GK, Boehm E, Clark JF (1996) Effects of treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor trandolapril and the calcium antagonist verapamil on the sensitivity of glucose metabolism to insulin in rat soleus muscle in vitro.  Diabetes 45 (supplement 1): S120-S124. PMID: 8529792
  2. Young ME, Leighton B, Radda GK (1996) Glycogen phosphorylase may be activated by AMP-kinase in skeletal muscle.  Biochem Soc Trans 24: 268S. PMID: 8736926
  3. Young ME, Radda GK, Leighton B (1996) Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR - an activator of AMP-activated protein kinase.  FEBS Lett 382: 43-47. PMID: 8612761
  4. Young ME, Clark JF, Leighton B (1997) Zaprinast raises glucose utilization in SHR skeletal muscle.  Biochem Soc Trans 25: 401S. PMID: 9388631
  5. Young ME, Clark JF, Leighton B (1997) NOS activity in skeletal muscle from hypertensive rats.  Biochem Soc Trans 25: 400S. PMID: 9388630
  6. Dimitriadis GD, Leighton B, Parry-Billings M, Sasson S, Young ME, Krause U, Bevan S, Piva T, Wegener G, Newsholme EA (1997) The effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle.  Biochem J 321: 707-712. PMID: 9032457
  7. Young ME, Radda GK, Leighton B (1997) Nitric oxide stimulates glucose transport and metabolism in rat skeletal muscle in vitro.  Biochem J 322: 223-228. PMID: 9078265
  8. Young ME, Leighton B (1998) Evidence for altered sensitivity of the nitric oxide/cGMP signaling cascade in insulin resistant skeletal muscle.  Biochem J 329: 73-79. PMID: 9405277
  9. Young ME, Leighton B (1998) Fuel oxidation in skeletal muscle is stimulated by nitric oxide/cGMP; evidence for involvement of cGMP-dependent protein kinase.  FEBS Lett 424: 79-83. PMID: 9537519
  10. Andersson U, Leighton B, Young ME, Blomstrand E, Newsholme EA (1998) Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide.  Biochem Biophys Res Commun 249: 512-516. PMID: 9712727
  11. Willott CA, Young ME, Leighton B, Kemp GJ, Boehm EA, Radda GK, Clarke K (1999) Creatine uptake in isolated soleus muscle: kinetics and dependence on sodium, but not on insulin.  Acta Phyiol Scand 166: 99-104. PMID: 10383488
  12. Bia BL, Cassidy PJ, Young ME, Rafael JA, Leighton B, Davies KE, Radda GK, Clarke K (1999) Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.  J Mol Cell Cardiol 31: 1857-1862. PMID: 10525423
  13. Gibala MJ, Young ME, Taegtmeyer H (2000) Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle.  Acta Physiol Scand 168: 657-665. PMID: 10759602
  14. Depre C, Young ME, Ying J, Singh Ahuja H, Han Q, Garza N, Davies PJA, Taegtmeyer H (2000) Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction.  J Mol Cell Cardiol 32: 985-996. PMID: 10888252
  15. Dean DJ, Daugaard JR, Young ME, Saha AK, Vavav D, Asp S, Kiens B, Kim K, Witters LA, Richter EA, Ruderman NB (2000) Exercise diminishes the activity of acetyl CoA carboxylase in human muscle.  Diabetes 49: 1295-1300. PMID: 10923628
  16. Young ME, Goodwin GW, Ying J, Guthrie P, Wilson CR, Laws FA, Taegtmeyer H (2001) Induction of cardiac and skeletal muscle malonyl-CoA decarboxylase by fatty acids.  Am J Physiol Endocrinol Metab 280: E471-E479. PMID: 11171602
  17. Young ME, Patil S, Ying J, Depre C, Singh Ahuja H, Shipley GL, Stepkowski SM, Davies PJA, Taegtmeyer H (2001) Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart.  FASEB J 15: 833-845. PMID: 11259402
  18. Kaushik VK, Young ME, Dean DJ, Kurowski TG, Saha AK, Ruderman NB (2001) Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR.  Am J Physiol Endocrinol Metab 281: E335-E340. PMID: 11440910
  19. Young ME, Razeghi P, Taegtmeyer H (2001) Clock genes in the heart: characterization and attenuation with hypertrophy.  Circ Res 88: 1142-1150. PMID: 11397780
  20. Razeghi P, Young ME, Abbasi S, Taegtmeyer H (2001) Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart.  Biochem Biophys Res Commun 287: 5-10. PMID: 11549245
  21. Young ME, Okerberg KA, Wilson CR, Deferrari DA, Ying J, Guthrie PH, Razeghi P, Clubb Jr. FJ, Taegtmeyer H (2001) Calcitonin gene-related peptide is not essential for the development of pressure overload-induced hypertrophy in vivo.  Mol Cell Biochem 225: 43-49. PMID: 11716363
  22. Young ME, Laws FA, Goodwin GW, Taegtmeyer H (2001) Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in rat hypertrophied heart.  J Biol Chem 276: 44390-44395. PMID: 11574533
  23. Young ME, Razeghi P, Cedars AM, Guthrie PH, Taegtmeyer H (2001)  Intrinsic diurnal variations in cardiac metabolism and contractile function.  Circ Res 89: 1199-1208. PMID: 11739286
  24. Razeghi P, Young ME, Alcorn JL, Moravec CS, Frazier OH, Taegtmeyer H (2001) Metabolic gene expression in fetal and failing human heart.  Circulation 104: 2923-2931. PMID: 11739307
  25. Young ME, Wilson CR, Razeghi P, Guthrie PH, Taegtmeyer H (2002) Alterations of the circadian clock in the heart by streptozotocin-induced diabetes.  J Mol Cell Cardiol 34: 223-231. PMID: 11851361
  26. Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED (2002) Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.  J Clin Invest 109: 629-639. PMID: 11877471
  27. Taegtmeyer H, Razeghi P, Young ME (2002) Mitochondrial proteins in hypertrophy and atrophy: a transcript analysis in rat heart.  Clin Exp Pharmacol Physiol 29: 346-350. PMID: 11985548
  28. Taegtmeyer H, McNulty P, Young ME (2002) Adaptation and maladaptation of the heart in diabetes: Part I: General concepts.  Circulation 105: 1727-1733. PMID: 11940554
  29. Young ME, McNulty P, Taegtmeyer H (2002) Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms.  Circulation 105: 1861-1870. PMID: 11956132
  30. Razeghi P, Young ME, Cockrill TC, Frazier OH, Taegtmeyer H (2002) Downregulation of myocardial myocyte enhancer factor 2C and myocyte enhancer factor 2C regulated gene expression in diabetic patients with non-ischemic heart failure.  Circulation 106: 407-411. PMID: 12135937
  31. Razeghi P, Young ME, Ying J, Depre C, Uray IP, Kolesar J, Shipley GL, Moravec CS, Davies PJA, Frazier OH, Taegtmeyer H (2002) Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading.  Cardiology 97: 203-209. PMID: 12145475
  32. Young ME, Guthrie PH, Razeghi P, Leighton B, Abbasi S, Patil S, Taegtmeyer H (2002) Impaired long chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.  Diabetes 51: 2587-2595. PMID: 12145175
  33. Wen HY, Xia Y, Young ME, Taegtmeyer H, Kellems RE (2002) The adenylosuccinate synthetase-1 gene is activated in the hypertrophied rodent heart.  J Cell Mol Med 6: 235-243. PMID: 12169208
  34. Xia Y, Wen HY, Young ME, Gurthrie PH, Taegtmeyer H, Kellems RE (2003) mTOR and PKA signaling mediate the cardiac transcriptional response to glutamine.  J Biol Chem 278: 13143-13150. PMID: 12522136
  35. Young ME (2003) Circadian Rhythms in Cardiac Gene Expression.  Curr Hypertension Reports 5:  445-453. PMID: 14594562
  36. Essop MF, Razeghi P, McLeod C, Young ME, Taegtmeyer H, Sack MN (2004) Hypoxia-induced decrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling.  Biochem Biophys Res Commun 314: 561-564. PMID: 14733944
  37. Lei B, Lionetti V, Young ME, Chandler MP, d'Agostino C, Kang E, Altarejos M, Matsuo K, Hintze TH, Stanley WC, Recchia FA (2004) Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure.  J Mol Cell Cardiol 36: 567-576. PMID: 15081316
  38. Chan AY, Soltys CL, Young ME, Proud CG, Dyck JR (2004) Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.  J Biol Chem 279: 32771-32779. PMID: 15159410
  39. Stavinoha MA, RaySpellicy JW, Essop MF, Graveleau C, Abel ED, Hart-Sailors ML, Mersmann HJ, Bray MS, Young ME (2004) Evidence for Mitochondrial Thioesterase 1 as a Peroxisome Proliferator-Activated Receptor alpha Regulated Gene in Cardiac and Skeletal Muscle.  American Journal of Physiology, Endocrinology and Metabolism 287: E888-895. PMID: 15292030
  40. Stavinoha MA, RaySpellicy JW, Hart-Sailors ML, Mersmann HJ, Bray MS, Young ME (2004) Diurnal Variations in the Responsiveness of Cardiac and Skeletal Muscle to Fatty Acids. American Journal of Physiology, Endocrinology and Metabolism 287: E878-E887. PMID: 15292029
  41. Golfman LS, Wilson CR, Sharma S, Burgmaier M, Young ME, Guthrie PH, Van Arsdall M, Adrogue JV, Brown KK, Taegtmeyer H (2005) Activation of PPAR{gamma} enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats.   American Journal of Physiology, Endocrinology and Metabolism 289: E328-E336. PMID: 15797988
  42. Lionetti V, Linke A, Young ME, Chandler MP, d'Agostino C, Kang, E, Altarejos, M, Matsuo, K, Hintze TH, Stanley WC, Recchia FA (2005) Carnitine Palmitoyl Transferase-I Inhibition Prevents Left Ventricular Remodeling, Down-regulation of Metabolic Genes, and Delays the Onset of Decompensation in Pacing-Induced Heart Failure.  Cardiovascular Research 66: 454-461. PMID: 15914110
  43. Durgan DJ, Hotze MA, Tomlin TM, Egbejimi O, Graveleau C, Abel ED, Shaw CA, Bray MS, Hardin PE, Young ME (2005) The intrinsic circadian clock within the cardiomyocyte.  American Journal of Physiology Heart and Circulatory Physiology 289: H1530-H1541. PMID: 15937094
  44. McClure TD, Young ME, Taegtmeyer H, Ning XH, Buroker NE, Lopez-Guisa J, Portman MA (2005) Thyroid hormone Interacts with PPAR-a and PGC-1 during mitochondrial maturation in sheep heart. American Journal of Physiology Heart and Circulatory Physiology 289: H2258-H2264. PMID: 16024569
  45. Boudina S, Sena S, O’Neill BT, Tathireddy P, Young ME, Abel ED (2005) Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impairs myocardial energetics in obesity.  Circulation 112: 2686-2695. PMID: 16246967
  46. Morgan EE, Rennison JH, Young ME, McElfresh TA, Kung TA, Tserng KY, Hoit BD, Stanley WC, Chandler MP (2006) Effects of Chronic Activation of Peroxisome Proliferator Activated Receptor Alpha or High Fat Feeding in a Rat Infarct Model of Heart Failure.  American Journal of Physiology Heart and Circulatory Physiology 290: H1899-H1904. PMID: 16339830
  47. Young ME (2006) The Circadian Clock Within the Heart: Potential Influence on Myocardial Gene Expression, Metabolism and Function.  American Journal of Physiology Heart and Circulatory Physiology 290: H1-H16. PMID: 16373589
  48. Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Dyck JB, Abel ED, Young ME (2006) Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.  American Journal of Physiology Heart and Circulatory Physiology. 290:H2480-H2497. PMID: 16428347
  49. Razeghi P, Baskin, KK, Sharma S, Young ME, Stepkowski S, Essop FM, Taegtmeyer H (2006) Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart.  Biochem Biophy Res Commun 342: 361-364. PMID: 16483544
  50. Okere IC, Chandler MP, McElfresh T, Rennison J, Sharov V, Sabbah HN, Tserng KY, Hoit BD, Ernsberger P, Young ME, Stanley WC (2006) Differential Effects of Saturated and Unsaturated Fatty Acid Diets on Cardiomyocyte Apoptosis, Adipose Distribution, and Serum Leptin.  American Journal of Physiology Heart and Circulatory Physiology.  291: H38-H44. PMID: 16443671
  51. Morgan EE, Chandler MP, Young ME, McElfresh TA, Kung TA, Hoit BD, Stanley WC (2006) Dissociation Between Gene and Protein Expression of Metabolic Enzymes in a Rodent Model of Heart Failure.  Eur J Heart Failure 8: 687-693. PMID: 16513421
  52. Li J, Coven DL, Miller EJ, Hu X, Young ME, Sinusas AJ, Carling D, Young LH (2006) Activation of AMPK (alpha)- and (gamma)- Complexes in the Intact Ischemic Rat Heart.  American Journal of Physiology Heart and Circulatory Physiology 291: H1927-34. PMID: 16648175
  53. Durgan DJ, Trexler N, Egbejimi O, Bray MS, Hardin PE, Chandler M, Chow CW, Young ME (2006) The Circadian Clock Within the Cardiomyocyte is Essential for Responsiveness of the Heart to Fatty Acids.  J. Biol. Chem. 281; 24254-24269. PMID: 16798731
  54. Gupte SA, Levine R, Young ME, Gupte RS, Lionetti V, Labinskyy V, Floyd B, Bellomo M, Wolin MS, Recchia FA (2006) Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.  Journal of Molecular and Cellular Cardiology 41: 340-9. PMID: 16828794
  55. Morgan EE, Young ME, McElfresh TA, Kung TA, Hoit BD, Chandler MP, Stanley WC (2006) Chronic Treatment with Trimetazidine Reduces the Up-Regulation of Atrial Natriuetic Peptide in Heart Failure.  Fundamental and Clinical Pharmacology 20: 503-505. PMID: 16968422
  56. Okere IC, Young ME, McElfresh TA, Chess DJ, Sharov VG, Sabbah HN, Hoit BD, Ernsberger P, Chandler MP, Stanley WC (2006) Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension.  Hypertension 48: 1116-1123. PMID: 17060511
  57. Zanquetta MM, Nascimento MEC, Mori RCT, Schaan BD, Young ME, Machado UF (2006) Participation of beta-adrenergic activity in modulation of GLUT4 expression during fasting and refeeding in rats.  Metabolism 55: 1538-1545. PMID: 17046558
  58. Dyck JR, Hopkins TA, Bonnet S, Michelakis ED, Young ME, Watanabe M, Kawase Y, Jishage K, Lopaschuk GD (2006) Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury.  Circulation 114: 1721-1728. PMID: 17030679
  59. Buroker NE, Young ME, Wei C, Serikawa K, Ge M, Ning XH, Portman MA (2007) The dominant negative thyroid hormone receptor beta-mutant {Delta}337T alters PPAR{alpha} signaling in heart.  Am J Physiol Endocrinol Metab 292: E453-E460. PMID: 16985257
  60. Labinskyy V, Bellomo M, Chandler MP, Young ME, Lionetti V, Qanud K, Bigazzi F, Sampietro T, Stanley WC, Recchia FA (2007) Chronic activation of peroxisome proliferator-activated receptor-alpha with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure.  J Pharmacol Exp Ther 321: 165-171. PMID: 17215446
  61. King KL, Young ME, Kerner J, Huang H, O’shea KM, Alexson SE, Hoppel CL, Stanley WC (2007) Diabetes and activation of peroxisome proliferator activated receptor alpha increase mitochondrial thioesterase I protein expression and activity in the heart.  J Lipid Res 48: 1511-1517. PMID: 17438340
  62. Bray MS, Young ME (2007) Circadian Rhythms in the Development of Obesity: Potential Role for the Circadian Clock within the Adipocyte.  Obesity Reviews 8: 169-181. PMID: 17300281
  63. Okere IC, Chandler MP, McElfresh TA, Rennison JH, Kung TA, Hoit BD, Ernsberger P, Young ME, Stanley WC (2007) Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high fat diet.  Clinical and Experimental Physiology and Pharmacology 34: 113-119. PMID: 17201745
  64. Young ME, Bray MS (2007) Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction.  Sleep Med 8: 656-667. PMID: 17387040
  65. Chandler MP, Morgan EE, McElfresh TA, Kung TA, Rennison JH, Hoit BD, Young ME (2007) Heart Failure Progression is Accelerated Following Myocardial Infarction In Type II Diabetic Rats.  American Journal of Physiology Heart and Circulatory Physiology 293: H1609-1616. PMID: 17545473
  66. Khairallah M, Khairallah R, Young ME, Dyck JRB, Petrof BJ, Des Rosiers C (2007) Metabolic and Signaling Alterations in Dystrophin-Deficient Hearts Precede Overt Cardiomyopathy.  Journal of Molecular and Cellular Cardiology 43: 119-129. PMID: 17583724
  67. Wilson CR, Tran MK, Salazar KL, Young ME, Taegtmeyer H (2007) Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem J 406: 457-467. PMID: 17550347
  68. Durgan DJ, Moore MW, Ha NP, Egbejimi O, Fields A, Mbawuike U, Egbejimi A, Shaw CA, Bray MS, Nannegari V, Hickson-Bick DL, Heird WC, Dyck JRB, Chandler MP, Young ME (2007) Circadian rhythms in myocardial metabolism and contractile function; influence of workload and oleate.  American Journal of Physiology Heart and Circulatory Physiology 293: H2385-H2393. PMID: 17616739
  69. Zungu M, Alcolea MP, Garcia-Palmer FJ, Young ME, Essop MF (2007) Genomic Modulation of Mitochondrial Respiratory Genes in the Hypertrophied Heart Reflects Adaptive Changes in Mitochondrial and Contractile Function.  American Journal of Physiology Heart and Circulatory Physiology 293:H2819-2825. PMID: 17704287
  70. Koonen DPY, Febbraio M, Bonnet S, Nagendran J, Young ME, Michelakis ED, Dyck JRB (2007) CD36 expression contributes to age-induced cardiomyopathy in mice.  Circulation 116: 2139-2147. PMID: 17967771
  71. Koonen DPY, Jacobs RL, Febbraio M, Young ME, Soltys CL, Ong H, Vance DE, Dyck JRB (2007) Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated with Diet-Induced Obesity.  Diabetes: 56: 2863-2871. PMID: 17728375
  72. Folmes KD, Witters LA, Allard MF, Young ME, Dyck JRB (2007) The AMPK gamma R70Q mutant regulates multiple metabolic and growth pathways in neonatal cardiac myocytes.  American Journal of Physiology Heart and Circulatory Physiology: 293: H3456-64. PMID: 17906100
  73. Kung TA, Egbejimi O, Cui J, Durgan DJ, Shaw CA, Hardin PE, Stanley WC, Young ME  (2007) Rapid attenuation of circadian clock gene oscillations in the rat heart following myocardial ischemia.  Journal of Molecular and Cellular Cardiology: 43: 744-753. PMID: 17959196
  74. Young ME, Yan J, Razeghi P, Cooksey RC, Guthrie PH, Stepkowski SM, McClain DA, Tian R, Taegtmeyer H (2007) Proposed regulation of gene expression by glucose in rodent heart.  Gene Regulation and Systems Biology: 1: 251-262. PMID: 19936093
  75. Bray MS, Shaw CA, Moore MWS, Garcia RAP, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai J, Bugger H, Zhang D, Rohwasser A, Rennison JH, Dyck JRB, Litwin SE, Hardin P, Chow CW, Chandler MP, Abel ED, Young ME (2008) Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression.  American Journal of Physiology Heart and Circulatory Physiology: 294: H1036-H1047. PMID: 18156197
  76. Garcia R, Afeche SC, Scialfa JH, Amaral FG, Santos SH, Lima FB, Young ME, Cipolla-Neto J (2008) Insulin modulates norepinephrine-mediated melatonin synthesis in cultured rat pineal gland.  Life Sci: 82: 108-114. PMID: 18048060
  77. Gélinas R, Labarthe F, Bouchard B, Mc Duff J, Charron G, Young ME, Des Rosiers C (2008) Alterations in carbohydrate metabolism and its regulation in PPAR alpha null mouse hearts.  American Journal of Physiology Heart and Circulatory Physiology: 294: H1571-H1580. PMID: 18223187
  78. Khairallah M, Khairallah R, Young ME, Allen BG, Gillis MA, Danialou G, Deschepper C, Petrof BJ, Des Rosiers C (2008) Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency.  PNAS: 105: 7028-7033. PMID: 18474859
  79. Lockridge JB, Sailors M, Durgan DJ, Egbejimi O, Jeong WJ, Bray MS, Stanley WC, Young ME (2008) Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids.  J Lipid Res: 49: 1395-1408. PMID: 18387886
  80. Bray MS, Young ME (2008) Diurnal variations in myocardial metabolism.  Cardiovascular Res: 79: 228-237. PMID: 18304930
  81. Rennison JH, McElfresh TA, Okere IC, Patel HV, Foster AB, Patel KK, Stoll M, Minkler P, Fujioka H, Hoit BD, Young ME; Hoppel CL, Chandler MP (2008) Enhanced Acyl-CoA Dehydrogenase Activity is Associated with Improved Mitochondrial and Contractile Function in Heart Failure.  Cardiovascular Res: 79: 331-340. PMID: 18339649
  82. Durgan DJ, Young ME (2008) Linking the cardiomyocyte circadian clock to myocardial metabolism.  Cardiovascular Drugs and Therapy: 22: 115-124. PMID: 18274886
  83. Khairallah R, Khairallah M, Young ME, Allen BG, Lopaschuk GD, Deschepper CF, Des Rosiers C (2008) Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulation.  Journal of Molecular and Cellular Cardiology: 45: 230-239. PMID: 18590915
  84. Zungu M, Young ME, Stanley WC, Essop MF (2008) Expression of mitochondrial regulatory genes parallels respiratory capacity and contractile function in a rat model of hypoxia-induced right ventricular hypertrophy.  Mol Cell Biochem: 318: 175-181. PMCID: PMC2673516
  85. Yan J, Young ME, Cui L, Lopaschuk, GD, Liao R, Tian R (2009)  Increased glucose uptake and oxidation in mouse hearts prevents high fatty acid oxidation but causes cardiac dysfunction in diet induced obesity.  Circulation: 119: 2818-2828. PMCID: PMC2765220
  86. Young ME (2009) Anticipating anticipation: Pursuing identification of cardiomyocyte circadian clock function.  J Appl Physiol: 107: 1339-1347. PMCID: PMC2763844
  87. Esser KA, Young ME (2009) The role of clock genes in cardiometabolic disease.  J Appl Physiol: 107: 1316-1317. PMCID: PMC3329970
  88. Bray MS, Young ME (2009) The role of cell-specific circadian clocks in metabolism and disease.  Obesity Reviews: Suppl 2: 6-13. PMID: 19849797
  89. Tsai J, Young ME (2009) Diurnal variations in myocardial metabolism.  Heart and Metabolism: 44: 5-9.
  90. Zungu M, Young ME, Stanley WC, Essop MF (2009) Chronic treatment with the peroxisome proliferator-activated receptor alpha agonist Wy-14,643 attenuates myocardial respiratory capacity and contractile function. Mol Cell Biochem: 330: 55-62. PMID: 19360380
  91. Tsai JY, Kienesberger PC, Pulinilkunnil T, Sailors MH, Durgan DJ, Villegas-Montoya C, Jahoor A, Gonzalez R, Garvey ME, Boland B, Blasier Z, McElfresh TA, Nannegari V, Chow CW, Heird WC, Chandler MP, Dyck JR, Bray MS, Young ME (2010) Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock.  J Biol Chem: 285; 2918-2929. PMCID: PMC2823428
  92. Durgan DJ, Pulinilkunnil T, Villegas-Montoya C, Garvey ME, Frangogiannis NG, Michael LH, Chow CW, Dyck JR, Young ME (2010) Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. Circ Res: 106: 546-550.  PMCID: PMC3021132
  93. Durgan DJ, Young ME (2010) The cardiomyocyte circadian clock: Emerging roles in health and disease.  Circ Res: 106; 647-658. PMCID: PMC3223121
  94. Bray MS, Tsai JY, Villegas-Montoya C, Boland BB, Blasier Z, Egbejimi O, Kueht M, Young ME (2010) Time-of-Day-Dependent Dietary Fat Consumption Influences Multiple Cardiometabolic Syndrome Parameters in Mice.  Int J Obes: 34: 1589-1598 PMCID: PMC3021134.
  95. Burgmaier M, Philip F, Wilson CR, Sen S, Miller CC, Young M, Taegtmeyer H (2010) Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high fat “Western” diet.  Obesity: 18: 1895-901. PMCID: PMC3623948
  96. Berthiaume JM, Bray MS, McElfresh TA, Chen X, Azam SM, Young ME, Hoit BD, Chandler MP (2010) Myocardial contractile response to physiological stress improves with high saturated fat feeding in heart failure.  American Journal of Physiology Heart and Circulatory Physiology: 299; H410-421. PMCID: PMC2930388
  97. Bray MS, Young ME (2011) Direct Regulation of Fatty Acid Metabolism by Cell Autonomous Circadian Clocks: Time to Fatten up on Information?  J Biol Chem: 286; 11883-11889. PMCID: PMC3069390
  98. Durgan DJ, Tsai J, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JRB, Bray MS, Gamble KL, Gimble JM, Young ME (2011) Evidence Suggesting that the Cardiomyocyte Circadian Clock Modulates Responsiveness of the Heart to Hypertrophic Stimuli in Mice.  Chronobiology International: 28; 187-203. PMCID: PMC3230077
  99. Ko ML, Shi L, Tsai JY, Young ME, Neuendorff N, Earnest DJ, Ko GY (2011) Cardiac-Specific Mutation of Clock Alters the Quantitative Measurements of Physical Activities without Changing Behavioral Circadian Rhythms.  J Biol Rhythms: 26; 412-422. PMCID: PMC3181102
  100. Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai J, Grenett MH, Ratcliffe WF, Brewer RA, Villegas-Montoya C, Zou C, Zou L, Bray MS, Gamble KL, Chatham JC, Young ME (2011) O-GlcNAcylation: A Novel Post-Translational Modification Linking Myocardial Metabolism and the Cardiomyocyte Circadian Clock.  JBC: 286; 44606-44619. PMCID: PMC3247942
  101. Kienesberger PC, Pulinilkunnil T, Sung MMY, Haemmerle G, Kershaw EE, Young ME,   Light PE, Oudit GY, Zechner R, Dyck JRB (2012) Myocardial ATGL Over-expression Improves Systolic Function and Protects Against Pressure Overload-Induced Cardiac Dysfunction.  MCB: 32; 740-750. PMCID: PMC3272983
  102. Berthiaume JM, Young ME, Chen X, McElfresh T, Yu X, Chandler MP (2012) Normalizing the metabolic phenotype after myocardial infarction; impact of subchronic high fat feeding. J Mol Cell Card: 53; 125-133. PMCID: PMC3372615
  103. Jones LW, Antonelli J, Masko EM, Broadwater G, Lascola CD, Fels D, Dewhirst MW, Dyck JR, Nagendran J, Flores CT, Betof AS, Nelson ER, Pollak M, Dash RC, Young ME, Freedland SJ (2012) Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer. J Appl Physiol: 113; 263-272. PMCID: PMC3404704
  104. Cha-Molstad H, Xu G, Chen J, Jing G, Young ME, Chatham JC, Shalev A (2012) Calcium Channel Blockers Act through Nuclear Factor Y to Control Transcription of Key Cardiac Genes.  Mol Pharmacol. 82; 541-549. PMCID: PMC3422702
  105. Chatham JC, Young ME (2012) Metabolic remodeling in the hypertrophic heart: fuel for thought.  Circ Res. 111; 666-668. PMCID: PMC3462817
  106. Kozak LP, Young ME (2012) Heat from calcium cycling melts fat.  Nature Medicine: 18: 1458-1459. PMID: 23042344
  107. Bray MS, Young ME (2012) Chronobiological Effects on Obesity. Current Obesity Reports: 1: 9-15. PMCID: PMC3653336
  108. Chatham JC, Young ME (2013) Regulation of myocardial metabolism by the cardiomyocyte circadian clock. J Mol Cell Cardiol: 55: 139-46. PMCID: PMC4107417
  109. Bray MS, Ratcliffe WF, Grenett MH, Brewer RA, Gamble KL, Young ME (2013) Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice. Int J Obes (Lond).: 37: 843-852. PMCID: PMC3505273
  110. Tsai JY, Villegas-Montoya C, Boland BB, Blasier Z, Egbejimi O, Gonzalez R, Kueht M, McElfresh TA, Brewer RA, Chandler MP, Bray MS, Young ME (2013) Influence of dark phase restricted high fat feeding on myocardial adaptation in mice. J Mol Cell Cardiol; 55: 147-155. PMCID: PMC3546154
  111. Gamble KL, Young ME (2013) Metabolism as an Integral Cog in the Mammalian Circadian Clockwork.  Critical Reviews in Biochemistry and Molecular Biology: 48: 317-331PMCID: PMC3862897
  112. Nagendran J, Kienesberger PC, Pulinilkunnil T, Zordoky B, Young ME, Zechner R, Dyck JRB (2013) Cardiomyocyte Specific Adipose Triglyceride Lipase Overexpression Prevents Doxorubicin Induced Cardiac Dysfunction in Female Mice.  Heart: 99: 1041-1047.  PMID: 23704323
  113. Pulinilkunnil T, Kienesberger PC, Nagendran J, Waller TJ, Young ME, Kershaw EE, Korbutt G, Haemmerle G, Zechner R, Dyck JRB (2013) Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From Development of Lipotoxic Cardiomyopathy.  Diabetes: 62: 1464-1477. PMCID: PMC3636613
  114. Kienesberger PC, Pulinilkunnil T, Nagendran J, Young ME, Bogner-Strauss JG, Hackl H, Khadour R, Heydari E, Haemmerle G, Zechner R, Kershaw EE, Dyck JR (2013) Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation. Cardiovasc Res.: 99: 442-51 PMCID: PMC3718322
  115. Dolinsky VW, Rogan KJ, Sung MM, Zordoky BN, Haykowsky MJ, Young ME, Jones LW, Dyck JR (2013) Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice. Am J Physiol Endocrinol Metab.: 305: E243-E253.  PMCID: PMC4116416
  116. du Pré BC, van Veen TAB, Young ME, Vos MA, Doevendans PA, van Laake LW (2013) Circadian Rhythms in Cell Maturation.  Physiology: In Press.  PMID: 24382873
  117. Wende AR, Young ME (2013) APpEaLINg Therapeutic Target for Obesity Cardiomyopathy? J Mol Cell Cardiol: In Press.  PMID: 23948484
  118. Filiano AN, Millender-Swain T, Johnson R, Young ME, Gamble KL, Bailey SM (2013) Ethanol-induced circadian desynchrony is a potential contributor to the development of alcoholic fatty liver injury. PLoS ONE: 2013 Aug 12;8: e71684.  PMCID: PMC3741117
  119. Collins HE, HE L, Zou L, Qu J, Zhou L, Litovsky SH, Yang Q, Young ME, Marchase RB, Chatham JC  (2014)  Stromal interaction molecule 1 is essential for naormal cardiac homeostasis through modulation of ER and mitochondrial function.  Am J Physiol Heart Circ Physiol. 306:H1231-9. PMCID: PMC3989749
  120. Young ME (2014) PAI at breakfast (whether you like it or not).  Blood 123: 466-468.  PMID: 24458277
  121. Pulinilkunnil T, Kienesberger PC, Nagendran J, Sharma N, Young ME, Dyck JR (2014) Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity. Int J Obes (Lond). 2014 Feb;38(2):205-15. PMID: 23817015
  122. Zhu Y, Hanafy MA, Killingsworth CR, Walcott GP, Young ME, Pogwizd SM (2014) Morning surge of ventricular arrhythmias in a new arrhythmogenic canine model of chronic heart failure is associated with attenuation of time-of-day dependence of heart rate and autonomic adaptation, and reduced cardiac chaos. PLoS One. 2014 Aug 20;9(8):e105379. PMCID: PMC4139365
  123. Mattox TA, Young ME, Rubel CE, Spaniel C, Rodriguez JE, Grevengoed TJ, Gautel M, Xu Z, Anderson EJ, Willis MS (2014) MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo.  J Bioenerg Biomembr. Epub ahead of print.  PMCID: PMC4047114
  124. Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze EV, Ratcliffe WF, Mackay A, Simpson JA, Wright DC, Kirby G, Young ME, Martino TA (2014) The Day/Night Proteome in the Murine Heart.  Am J Physiol Regul Integr Comp Physiol. 307: R121-R137. PMCID: PMC4101618 
  125. Gamble KL, Berry R, Frank SJ, Young ME (2014) Circadian clock control of endocrine factors.  Nat Rev Endocrinol. Epub ahead of print.  PMID: 24863387
  126. Bailey SM, Udoh US, Young ME (2014) Circadian regulation of metabolism.  J Endocrinol. Epub ahead of print.  PMCID: PMC4109003  
  127. Kim T, He L, Johnson MS, Li Y, Zeng L, Ding Y, Long Q, Moore FJ, Sharer JD, Nagy TR, Young ME, Wood PA, Yang Q (2014) Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance.  J Diabetes Metab.  5:361.
  128. Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, Gamble KL (2014) Cardiomyocyte-specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart. J Biol Rhythms.  29: 257-276. PMID: 25238855
  129. Martino TA, Young ME (2015) Influence of the Cardiomyocyte Circadian Clock on Cardiac Physiology and Pathophysiology. J Biol. Rhythms: 30: 183-205.
  130. Besing RC, Paul J, Hablitz LM, Rogers CO, Johnson R, Young ME, Gamble KL (2015) Circadian rhythmicity of active GSK3 isoforms modulates molecular clock gene rhythms.  J Biol. Rhythms: 30: 155-160.
  131. Udoh US, Swain TM, Filiano AN, Gamble KL, Young ME, Bailey SM (2015) Chronic ethanol consumption disrupts diurnal rhythms of hepatic glycogen metabolism in mice. Am J Physiol Gastrointest Liver Physiol. 308: G964-G974.
  132. Gamble KL, Young ME (2015) Circadian biology: the early bird catches the morning shift.  Curr Biol. 25: R269-R271.
  133. Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR (2015) AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.  Cardiovasc Res. 107: 235-45.
  134. Ingle K, Kain V, Goel M, Prabhu S, Young ME, Halade G (2015) Cardiomyocyte specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response and impaired resolution of inflammation. Am J Physiol Heart and Circulatory Physiology  309(11):H1827-36. 
  135. Peliciari-Garcia RA, Goel M, Aristorenas JA, Shah K, He L, Yang Q, Shalev A, Bailey SM, Prabhu SD, Chatham JC, Gamble KL, Young ME (2016) Altered Myocardial Metabolic Adaptation to Increased Fatty Acid Availability in Cardiomyocyte-Specific CLOCK Mutant Mice. BBA Mol Cell Biol Lipids 1860(10):1579-95.
  136. Joo J, Cox C, Kindred E, Lashinger L, Young ME, Bray MS (2016) The acute effects of time-of-day-dependent high fat feeding on whole body metabolic flexibility in mice.  International Journal of Obesity 40(9):1444-51.
  137. Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler JR, Holzhutter HG, Kizer JR, Lewandowski ED, Malloy CR, Neubauer S, Peterson L, Portman M, Recchia F, van Eyk J, Wang TJ (2016) Assessing Cardiac Metabolism.  Circ. Res 118(10):1659-701.
  138. Byrne N, Levasseur J, Sung, MM, Masson, G, Boisvenue J, Young ME, Dyck JRB (2016) Normalization of Cardiac Substrate Utilization and Left Ventricular Hypertrophy Precede Functional Recovery in Heart Failure Regression.  Cardiovascular Research 110(2):249-57.
  139. McGinnis GR, Young ME (2016) Circadian Regulation of Metabolic Homeostasis: Causes and Consequences.  Nature and Science of Sleep 8:163-80.
  140. He L, Hamm JA, Reddy A, Sams D, Peliciari-Garcia RA, McGinnis GR, Bailey SM, Chow CW, Rowe GC, Chatham JC, Young ME (2016) Biotinylation: A Novel Posttranslational Modification Linking Cell Autonomous Circadian Clocks with Metabolism. Am J Physiol Heart and Circulatory Physiology310(11):H1520-32.
  141. Chen J, Young ME, Chatham JC, Dell'Italia L, Shalev A (2016) TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling. Am J Physiol Heart and Circulatory Physiology311(1):H64-75.
  142. Young ME (2016) Temporal Partitioning of Cardiac Metabolism by the Cardiomyocyte Circadian Clock.  Experimental Physiology 101(8):1035-9.
  143. Wende AR, Young ME, Chatham JC, Zhang J, Soorappan R, Darley-Usmar VM (2016) Redox Biology and the Interface Between Bioenergetics, Autophagy and Circadian Control of Metabolism.  Free Radical Biology & Medicine 100:94-107.
  144. Peliciari-Garcia RA, Prévide RM, Grenett MH, Nunes MT, Young ME (2016) Interrelationship between 3,5,3’- triiodothyronine and the circadian clock in the rodent heart. Chronobiology International.  33(10):1444-1454.
  145. Evonuk KS, Prabhu SD, Young ME, DeSilva TM (2017) Myocardial ischemia/reperfusion impairs neurogenesis and hippocampal-dependent learning and memory.  Brain Behav Immun.  61:266-273.
  146. Loyd C, Liu Y, Kim T, Holleman C, Galloway J, Bethea M, Ediger BN, Swain TA, Stoffers DA, Rowe GC, Young ME, Steele C, Habegger KM, Hunter CS (2017) Ldb1 Regulates Energy Homeostasis During Diet-Induced Obesity.  Endocrinology.  158(5):1289-1297.
  147. Wende AR, Brahma MK, McGinnis GR, Young ME (2017) Metabolic Origins of Heart Failure.  JACC Heart Failure.  2(3):297-310.
  148. Young ME (2017) Circadian Control of Cardiac Metabolism: Physiologic Roles and Pathologic Implications.  Methodist DeBakey Cardiovascular Journal.  In Press.
  149. Rowe GC, Young ME (2017) VEGF-B: Friend or Foe to the Heart in Times of Nutrient Excess?  Am J Physiol Heart and Circulatory Physiology.  313(2):H244-H247.
  150. McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Abel ED, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, Chatham JC, Young ME (2017) Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.  J Mol Cell Cardiol.  110: 80-95.
  151. Peliciari-Garcia RA, Bargi-Souza P, Young ME, Nunes MT (2018) Repercussions of hypo and hyperthyroidism on the heart circadian clock. Chronobiol Int. 35(2):147-159.
  152. Udoh US, Valcin JA, Swain TM, Filiano AN, Gamble KL, Young ME, Bailey SM (2018)  Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice. Am J Physiol Gastrointest Liver Physiol. 314: G431-G447.
  153. Van Laake LW, Lüscher TF, Young ME (2018) The circadian clock in cardiovascular regulation and disease: Lessons from the Nobel Prize in Physiology or Medicine 2017. Eur Heart J. 39: 2326-2329.
  154. Brewer RA, Collins HE, Berry RD, Brahma MK, Tirado BA, Peliciari-Garcia RA, Stanley HL, Wende AR, Taegtmeyer H, Rajasekaran NS, Darley-Usmar V, Zhang J, Frank SJ, Chatham JC, Young ME (2018) Temporal Partitioning of Adaptive Responses of the Murine Heart to Fasting.  Life Sciences. 197: 30-39.  
  155. Kain VIngle KAKachman MBaum HShanmugam GRajasekaran NSYoung MEHalade GV (2018) Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation.  Am J Physiol Heart and Circulatory Physiology 314: H160-H169.
  156. Speed JS, Hyndman KA, Roth K, Heimlich JB, Kasztan M, Fox BM, Johnston JG, Becker BK, Jin C, Gamble KL, Young ME, Pollock JS, Pollock DM (2018) High dietary sodium causes dyssynchrony of the renal molecular clock in rats.  Am J Physiol Renal Physiology 314: F89-F98.
  157. Peliciari-Garcia RA, Darley-Usmar V, Young ME (2018) An overview of the emerging interface between cardiac metabolism, redox biology and the circadian clock.  Free Radic Biol Med. 119: 75-84.
  158. Young ME, Reddy AB, Pollock DM (2018) Introduction to special issue: Circadian regulation of metabolism, redox signaling and function in health and disease.  Free Radic Biol Med. 119: 1-2.
  159. Berry R, McGinnis GR, Banerjee RR, Young MEFrank SJ (2018) Differential tissue response to growth hormone in mice.  FEBS Open Bio. 8: 1146-1154.
  160. Kim TNason SHolleman CPepin MWilson LBerryhill TFWende ARSteele CYoung MEBarnes SDrucker DJFinan BDiMarchi RPerez-Tilve DTschöp MHabegger KM (2018) Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21.  Diabetes. 67: 1773-1782.
  161. Dunham-Snary KJ, Sandel MW, Sammy MJ, Westbrook DGXiao RMcMonigle RJRatcliffe WFPenn AYoung MEBallinger SW (2018) Mitochondrial - nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo.  EBioMedicine. 36: 316-328.
  162. Collins HE, Pat BM, Zou L, Litovsky SH, Wende AR, Young ME, Chatham JC (2019) Novel role of the ER/SR Ca2+ sensor, STIM1, in regulation of cardiac metabolism. Am J Physiol Heart Circ Physiol. 316: H1014-H1026.
  163. Resuehr D, Wu G, Johnson RL Jr, Young ME, Hogenesch JB, Gamble KL (2019) Shift Work Disrupts Circadian Regulation of the Transcriptome in Hospital Nurses. J Biol Rhythms. 34: 167-177.
  164. Daniels SR, Pratt CA, Hollister EB, Labarthe D, Cohen DA, Walker JR, Beech BM, Balagopal PB, Beebe DW, Gillman MW, Goodrich JM, Jaquish C, Kit B, Miller AL, Olds D, Oken E, Rajakumar K, Sherwood NE, Spruijt-Metz D, Steinberger J, Suglia SF, Teitelbaum SL, Urbina EM, Van Horn L, Ward D, Young ME (2019) Promoting Cardiovascular Health in Early Childhood and Transitions in Childhood through Adolescence: A Workshop Report.  J Pediatr. 209: 240-251.
  165. Young ME (2019) Metabolic Coupling as a Therapeutic Strategy for Heart Failure.  JACC Basic Transl Sci. 2019 Jun 24;4(3):401-403